Physical Properties | | | |
Molecular Weight: 360.505 g/mol | logS: -5.30672 | SlogP: 5.27502 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.10937 | Sterimol/B1: 4.18524 | Sterimol/B2: 4.2686 | Sterimol/B3: 4.6256 |
Sterimol/B4: 7.35986 | Sterimol/L: 15.8535 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.615 | Positive charged surface: 438.017 | Negative charged surface: 206.597 | Volume: 376 |
Hydrophobic surface: 566.178 | Hydrophilic surface: 78.437 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |