Physical Properties | | | |
Molecular Weight: 416.477 g/mol | logS: -5.82195 | SlogP: 4.0267 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0221113 | Sterimol/B1: 2.35816 | Sterimol/B2: 3.05552 | Sterimol/B3: 4.24841 |
Sterimol/B4: 7.4929 | Sterimol/L: 22.359 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 717.805 | Positive charged surface: 417.859 | Negative charged surface: 289.877 | Volume: 399.875 |
Hydrophobic surface: 604.231 | Hydrophilic surface: 113.574 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |