Physical Properties | | | |
Molecular Weight: 371.461 g/mol | logS: -2.51079 | SlogP: 2.612 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.120304 | Sterimol/B1: 3.33896 | Sterimol/B2: 5.19187 | Sterimol/B3: 5.36505 |
Sterimol/B4: 5.53975 | Sterimol/L: 14.8375 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 580.762 | Positive charged surface: 408.25 | Negative charged surface: 172.513 | Volume: 348.25 |
Hydrophobic surface: 444.225 | Hydrophilic surface: 136.537 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |