Physical Properties | | | |
Molecular Weight: 416.477 g/mol | logS: -5.35508 | SlogP: 5.1457 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.100509 | Sterimol/B1: 3.01453 | Sterimol/B2: 4.79033 | Sterimol/B3: 5.84197 |
Sterimol/B4: 7.60559 | Sterimol/L: 17.283 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 684.625 | Positive charged surface: 490.635 | Negative charged surface: 193.99 | Volume: 402.875 |
Hydrophobic surface: 643.191 | Hydrophilic surface: 41.434 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |