Physical Properties | | | |
Molecular Weight: 537.101 g/mol | logS: -6.31308 | SlogP: 5.3493 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0602942 | Sterimol/B1: 2.60335 | Sterimol/B2: 4.00483 | Sterimol/B3: 5.76266 |
Sterimol/B4: 10.1352 | Sterimol/L: 20.3655 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 772.857 | Positive charged surface: 426.911 | Negative charged surface: 345.946 | Volume: 478.25 |
Hydrophobic surface: 593.495 | Hydrophilic surface: 179.362 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |