Physical Properties | | | |
Molecular Weight: 460.533 g/mol | logS: -8.85537 | SlogP: 5.5152 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0180447 | Sterimol/B1: 2.35749 | Sterimol/B2: 4.91695 | Sterimol/B3: 6.89921 |
Sterimol/B4: 7.54563 | Sterimol/L: 21.7319 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 762.174 | Positive charged surface: 425.818 | Negative charged surface: 326.425 | Volume: 421.5 |
Hydrophobic surface: 595.183 | Hydrophilic surface: 166.991 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |