Physical Properties | | | |
Molecular Weight: 470.386 g/mol | logS: -6.32034 | SlogP: 5.3362 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0286396 | Sterimol/B1: 2.36939 | Sterimol/B2: 4.03855 | Sterimol/B3: 4.12678 |
Sterimol/B4: 7.26271 | Sterimol/L: 22.6515 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 719.084 | Positive charged surface: 336.003 | Negative charged surface: 383.081 | Volume: 384.5 |
Hydrophobic surface: 502.805 | Hydrophilic surface: 216.279 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |