Physical Properties | | | |
Molecular Weight: 404.323 g/mol | logS: -6.16643 | SlogP: 4.7691 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.028416 | Sterimol/B1: 3.61877 | Sterimol/B2: 3.61949 | Sterimol/B3: 3.96493 |
Sterimol/B4: 6.15052 | Sterimol/L: 19.5565 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 637.48 | Positive charged surface: 269.689 | Negative charged surface: 367.791 | Volume: 329 |
Hydrophobic surface: 446.968 | Hydrophilic surface: 190.512 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |