Physical Properties | | | |
Molecular Weight: 401.511 g/mol | logS: -4.94669 | SlogP: 4.0762 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0486263 | Sterimol/B1: 2.56765 | Sterimol/B2: 3.458 | Sterimol/B3: 4.92458 |
Sterimol/B4: 6.65648 | Sterimol/L: 19.4892 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.44 | Positive charged surface: 364.576 | Negative charged surface: 283.864 | Volume: 354.375 |
Hydrophobic surface: 482.791 | Hydrophilic surface: 165.649 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |