Physical Properties | | | |
Molecular Weight: 411.482 g/mol | logS: -4.38489 | SlogP: 3.23262 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0889202 | Sterimol/B1: 1.969 | Sterimol/B2: 3.78905 | Sterimol/B3: 4.56172 |
Sterimol/B4: 11.1567 | Sterimol/L: 19.0401 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 676.903 | Positive charged surface: 441.615 | Negative charged surface: 235.287 | Volume: 376.125 |
Hydrophobic surface: 570.761 | Hydrophilic surface: 106.142 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |