Physical Properties | | | |
Molecular Weight: 412.869 g/mol | logS: -4.38785 | SlogP: 2.391 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0629659 | Sterimol/B1: 2.51949 | Sterimol/B2: 4.3794 | Sterimol/B3: 5.41042 |
Sterimol/B4: 5.56128 | Sterimol/L: 19.0878 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 632.477 | Positive charged surface: 320.37 | Negative charged surface: 312.107 | Volume: 346.75 |
Hydrophobic surface: 539.05 | Hydrophilic surface: 93.427 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |