Physical Properties | | | |
Molecular Weight: 381.435 g/mol | logS: -6.15661 | SlogP: 4.5775 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0275719 | Sterimol/B1: 2.92346 | Sterimol/B2: 3.47809 | Sterimol/B3: 4.3486 |
Sterimol/B4: 9.86541 | Sterimol/L: 17.5654 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.63 | Positive charged surface: 338.75 | Negative charged surface: 303.967 | Volume: 368.5 |
Hydrophobic surface: 561.051 | Hydrophilic surface: 87.579 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |