Physical Properties | | | |
Molecular Weight: 354.362 g/mol | logS: -3.83684 | SlogP: 2.3129 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0845327 | Sterimol/B1: 2.76342 | Sterimol/B2: 3.17781 | Sterimol/B3: 5.23828 |
Sterimol/B4: 6.4512 | Sterimol/L: 18.9101 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 618.455 | Positive charged surface: 372.831 | Negative charged surface: 245.624 | Volume: 328.5 |
Hydrophobic surface: 436.028 | Hydrophilic surface: 182.427 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |