Physical Properties | | | |
Molecular Weight: 382.488 g/mol | logS: -6.94901 | SlogP: 4.36472 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0143878 | Sterimol/B1: 2.37973 | Sterimol/B2: 2.47776 | Sterimol/B3: 3.83538 |
Sterimol/B4: 7.00941 | Sterimol/L: 22.011 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.227 | Positive charged surface: 388.844 | Negative charged surface: 273.383 | Volume: 366.375 |
Hydrophobic surface: 482.04 | Hydrophilic surface: 180.187 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |