Physical Properties | | | |
Molecular Weight: 401.555 g/mol | logS: -5.86553 | SlogP: 4.1453 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0392276 | Sterimol/B1: 2.18963 | Sterimol/B2: 2.62995 | Sterimol/B3: 5.10539 |
Sterimol/B4: 10.3475 | Sterimol/L: 17.7931 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 661.172 | Positive charged surface: 401.109 | Negative charged surface: 260.063 | Volume: 377.125 |
Hydrophobic surface: 501.41 | Hydrophilic surface: 159.762 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |