Physical Properties | | | |
Molecular Weight: 459.255 g/mol | logS: -6.31125 | SlogP: 6.2505 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0431456 | Sterimol/B1: 3.16407 | Sterimol/B2: 4.26683 | Sterimol/B3: 4.95059 |
Sterimol/B4: 5.71498 | Sterimol/L: 20.686 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 681.558 | Positive charged surface: 276.496 | Negative charged surface: 405.062 | Volume: 364.625 |
Hydrophobic surface: 488.642 | Hydrophilic surface: 192.916 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |