Physical Properties | | | |
Molecular Weight: 421.493 g/mol | logS: -5.40913 | SlogP: 4.24652 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.126733 | Sterimol/B1: 2.33443 | Sterimol/B2: 4.00664 | Sterimol/B3: 5.00284 |
Sterimol/B4: 10.5312 | Sterimol/L: 16.6529 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 697.007 | Positive charged surface: 464.498 | Negative charged surface: 232.509 | Volume: 411 |
Hydrophobic surface: 559.643 | Hydrophilic surface: 137.364 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |