Physical Properties | | | |
Molecular Weight: 452.487 g/mol | logS: -5.43864 | SlogP: 2.5233 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0484539 | Sterimol/B1: 2.56137 | Sterimol/B2: 4.0335 | Sterimol/B3: 4.05645 |
Sterimol/B4: 11.5626 | Sterimol/L: 18.0387 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 715.293 | Positive charged surface: 381.358 | Negative charged surface: 333.934 | Volume: 398 |
Hydrophobic surface: 558.377 | Hydrophilic surface: 156.916 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |