Physical Properties | | | |
Molecular Weight: 375.403 g/mol | logS: -6.41002 | SlogP: 4.7731 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.089505 | Sterimol/B1: 2.418 | Sterimol/B2: 3.16842 | Sterimol/B3: 4.78248 |
Sterimol/B4: 11.8054 | Sterimol/L: 15.4065 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.984 | Positive charged surface: 353.842 | Negative charged surface: 305.143 | Volume: 353.875 |
Hydrophobic surface: 590.664 | Hydrophilic surface: 68.32 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |