Physical Properties | | | |
Molecular Weight: 400.434 g/mol | logS: -4.42274 | SlogP: 4.074 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.291235 | Sterimol/B1: 2.40807 | Sterimol/B2: 4.31976 | Sterimol/B3: 5.41793 |
Sterimol/B4: 8.62664 | Sterimol/L: 14.7273 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 622.636 | Positive charged surface: 401.38 | Negative charged surface: 221.256 | Volume: 379.375 |
Hydrophobic surface: 483.331 | Hydrophilic surface: 139.305 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |