Physical Properties | | | |
Molecular Weight: 454.44 g/mol | logS: -6.81835 | SlogP: 3.56498 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0133883 | Sterimol/B1: 2.58574 | Sterimol/B2: 2.61426 | Sterimol/B3: 3.0029 |
Sterimol/B4: 11.0664 | Sterimol/L: 16.1374 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 672.131 | Positive charged surface: 389.987 | Negative charged surface: 282.144 | Volume: 400.5 |
Hydrophobic surface: 489.056 | Hydrophilic surface: 183.075 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |