Physical Properties | | | |
Molecular Weight: 408.254 g/mol | logS: -6.33502 | SlogP: 5.2729 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0215572 | Sterimol/B1: 2.22976 | Sterimol/B2: 2.84381 | Sterimol/B3: 4.13169 |
Sterimol/B4: 6.78916 | Sterimol/L: 17.4548 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 583.622 | Positive charged surface: 192.379 | Negative charged surface: 391.242 | Volume: 296 |
Hydrophobic surface: 259.276 | Hydrophilic surface: 324.346 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |