Physical Properties | | | |
Molecular Weight: 458.559 g/mol | logS: -5.84358 | SlogP: 4.2501 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0541897 | Sterimol/B1: 3.08972 | Sterimol/B2: 4.28094 | Sterimol/B3: 6.06352 |
Sterimol/B4: 7.14899 | Sterimol/L: 22.0463 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 729.582 | Positive charged surface: 377.344 | Negative charged surface: 352.239 | Volume: 412.5 |
Hydrophobic surface: 566.906 | Hydrophilic surface: 162.676 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |