Physical Properties | | | |
Molecular Weight: 430.868 g/mol | logS: -5.7204 | SlogP: 4.0913 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.180214 | Sterimol/B1: 4.37443 | Sterimol/B2: 4.58051 | Sterimol/B3: 6.44886 |
Sterimol/B4: 6.4908 | Sterimol/L: 14.6342 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 639.834 | Positive charged surface: 305.173 | Negative charged surface: 334.661 | Volume: 359.75 |
Hydrophobic surface: 440.236 | Hydrophilic surface: 199.598 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |