Physical Properties | | | |
Molecular Weight: 374.396 g/mol | logS: -6.18663 | SlogP: 3.6154 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0674891 | Sterimol/B1: 2.79759 | Sterimol/B2: 3.52512 | Sterimol/B3: 4.16218 |
Sterimol/B4: 8.17054 | Sterimol/L: 18.3238 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.164 | Positive charged surface: 381.951 | Negative charged surface: 256.769 | Volume: 350.5 |
Hydrophobic surface: 523.513 | Hydrophilic surface: 125.651 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |