Physical Properties | | | |
Molecular Weight: 366.373 g/mol | logS: -4.96731 | SlogP: 2.4865 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0667062 | Sterimol/B1: 2.50986 | Sterimol/B2: 2.69726 | Sterimol/B3: 5.23976 |
Sterimol/B4: 8.03045 | Sterimol/L: 18.2588 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 627.771 | Positive charged surface: 369.533 | Negative charged surface: 258.238 | Volume: 337.5 |
Hydrophobic surface: 470.173 | Hydrophilic surface: 157.598 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |