Physical Properties | | | |
Molecular Weight: 409.486 g/mol | logS: -4.47212 | SlogP: 4.04092 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0460946 | Sterimol/B1: 2.56782 | Sterimol/B2: 3.23677 | Sterimol/B3: 4.10608 |
Sterimol/B4: 10.9631 | Sterimol/L: 20.4237 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 709.212 | Positive charged surface: 482.258 | Negative charged surface: 226.954 | Volume: 395.5 |
Hydrophobic surface: 536.722 | Hydrophilic surface: 172.49 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |