Physical Properties | | | |
Molecular Weight: 384.439 g/mol | logS: -5.00961 | SlogP: 3.18102 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0265785 | Sterimol/B1: 2.4502 | Sterimol/B2: 2.97664 | Sterimol/B3: 3.52051 |
Sterimol/B4: 10.7582 | Sterimol/L: 18.9085 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 677.223 | Positive charged surface: 425.646 | Negative charged surface: 251.577 | Volume: 370.375 |
Hydrophobic surface: 566.686 | Hydrophilic surface: 110.537 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |