Physical Properties | | | |
Molecular Weight: 404.853 g/mol | logS: -6.49482 | SlogP: 4.18597 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.084297 | Sterimol/B1: 2.84976 | Sterimol/B2: 3.87887 | Sterimol/B3: 4.00348 |
Sterimol/B4: 9.72805 | Sterimol/L: 15.4392 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 640.706 | Positive charged surface: 301.701 | Negative charged surface: 339.005 | Volume: 367.25 |
Hydrophobic surface: 563.148 | Hydrophilic surface: 77.558 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |