Physical Properties | | | |
Molecular Weight: 374.238 g/mol | logS: -3.56863 | SlogP: 3.14412 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0236476 | Sterimol/B1: 2.34226 | Sterimol/B2: 2.68055 | Sterimol/B3: 3.2773 |
Sterimol/B4: 6.61735 | Sterimol/L: 18.798 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 583.492 | Positive charged surface: 313.908 | Negative charged surface: 269.584 | Volume: 312.625 |
Hydrophobic surface: 503.741 | Hydrophilic surface: 79.751 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |