Physical Properties | | | |
Molecular Weight: 355.414 g/mol | logS: -3.74301 | SlogP: 1.3916 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.03947 | Sterimol/B1: 2.2403 | Sterimol/B2: 3.98422 | Sterimol/B3: 4.4171 |
Sterimol/B4: 5.97714 | Sterimol/L: 20.8623 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 629.222 | Positive charged surface: 470.027 | Negative charged surface: 159.195 | Volume: 345.875 |
Hydrophobic surface: 533.252 | Hydrophilic surface: 95.97 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |