Physical Properties | | | |
Molecular Weight: 386.407 g/mol | logS: -4.43863 | SlogP: 3.34722 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.129171 | Sterimol/B1: 3.03284 | Sterimol/B2: 4.92423 | Sterimol/B3: 5.36334 |
Sterimol/B4: 5.97333 | Sterimol/L: 16.5062 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 577.981 | Positive charged surface: 343.259 | Negative charged surface: 234.721 | Volume: 356.75 |
Hydrophobic surface: 427.451 | Hydrophilic surface: 150.53 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |