Physical Properties | | | |
Molecular Weight: 474.196 g/mol | logS: -6.98451 | SlogP: 6.0589 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0590498 | Sterimol/B1: 3.56198 | Sterimol/B2: 4.00796 | Sterimol/B3: 6.40866 |
Sterimol/B4: 6.58952 | Sterimol/L: 17.6668 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 668.026 | Positive charged surface: 272.143 | Negative charged surface: 383.653 | Volume: 377.25 |
Hydrophobic surface: 625.824 | Hydrophilic surface: 42.202 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |