Physical Properties | | | |
Molecular Weight: 468.189 g/mol | logS: -5.58308 | SlogP: 4.279 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0827044 | Sterimol/B1: 3.18215 | Sterimol/B2: 3.37604 | Sterimol/B3: 4.33556 |
Sterimol/B4: 9.56693 | Sterimol/L: 15.8735 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 635.915 | Positive charged surface: 322.692 | Negative charged surface: 302.216 | Volume: 365.375 |
Hydrophobic surface: 593.247 | Hydrophilic surface: 42.668 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |