Physical Properties | | | |
Molecular Weight: 433.552 g/mol | logS: -7.42814 | SlogP: 4.05804 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0342281 | Sterimol/B1: 2.83631 | Sterimol/B2: 3.72169 | Sterimol/B3: 4.40603 |
Sterimol/B4: 7.34059 | Sterimol/L: 21.6381 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 732.025 | Positive charged surface: 477.671 | Negative charged surface: 252.291 | Volume: 430 |
Hydrophobic surface: 558.695 | Hydrophilic surface: 173.33 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |