Physical Properties | | | |
Molecular Weight: 425.509 g/mol | logS: -5.88955 | SlogP: 2.3733 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0178199 | Sterimol/B1: 3.06548 | Sterimol/B2: 3.43635 | Sterimol/B3: 3.45762 |
Sterimol/B4: 8.50537 | Sterimol/L: 21.671 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 696.77 | Positive charged surface: 429.681 | Negative charged surface: 257.948 | Volume: 387.875 |
Hydrophobic surface: 503.688 | Hydrophilic surface: 193.082 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |