Physical Properties | | | |
Molecular Weight: 419.586 g/mol | logS: -4.07088 | SlogP: 1.10088 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0400214 | Sterimol/B1: 1.9962 | Sterimol/B2: 3.35311 | Sterimol/B3: 4.18044 |
Sterimol/B4: 10.5946 | Sterimol/L: 21.0277 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 765.544 | Positive charged surface: 632.436 | Negative charged surface: 133.108 | Volume: 445.125 |
Hydrophobic surface: 674.134 | Hydrophilic surface: 91.41 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |