Physical Properties | | | |
Molecular Weight: 434.54 g/mol | logS: -3.32779 | SlogP: 3.0183 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.110814 | Sterimol/B1: 3.0905 | Sterimol/B2: 3.29281 | Sterimol/B3: 5.4574 |
Sterimol/B4: 9.35089 | Sterimol/L: 18.5476 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 696.223 | Positive charged surface: 550.393 | Negative charged surface: 143.037 | Volume: 425.75 |
Hydrophobic surface: 617.214 | Hydrophilic surface: 79.009 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |