Physical Properties | | | |
Molecular Weight: 408.632 g/mol | logS: -2.91189 | SlogP: 0.7625 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0623718 | Sterimol/B1: 2.68522 | Sterimol/B2: 4.10925 | Sterimol/B3: 4.43006 |
Sterimol/B4: 5.75701 | Sterimol/L: 15.1052 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 555.773 | Positive charged surface: 302.293 | Negative charged surface: 247.393 | Volume: 301.625 |
Hydrophobic surface: 347.487 | Hydrophilic surface: 208.286 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |