Physical Properties | | | |
Molecular Weight: 483.394 g/mol | logS: -9.58212 | SlogP: 6.79522 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.147635 | Sterimol/B1: 2.45108 | Sterimol/B2: 3.32663 | Sterimol/B3: 6.06291 |
Sterimol/B4: 8.89293 | Sterimol/L: 17.1988 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 755.038 | Positive charged surface: 372.85 | Negative charged surface: 357.729 | Volume: 453 |
Hydrophobic surface: 680.738 | Hydrophilic surface: 74.3 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |