Physical Properties | | | |
Molecular Weight: 393.463 g/mol | logS: -5.5716 | SlogP: 4.28247 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0618792 | Sterimol/B1: 3.18885 | Sterimol/B2: 4.1295 | Sterimol/B3: 4.28243 |
Sterimol/B4: 7.49067 | Sterimol/L: 15.8141 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 642.833 | Positive charged surface: 332.271 | Negative charged surface: 300.83 | Volume: 362.375 |
Hydrophobic surface: 516.662 | Hydrophilic surface: 126.171 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |