Physical Properties | | | |
Molecular Weight: 402.447 g/mol | logS: -4.16588 | SlogP: 3.8599 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.022895 | Sterimol/B1: 2.26745 | Sterimol/B2: 2.93898 | Sterimol/B3: 4.2947 |
Sterimol/B4: 9.78419 | Sterimol/L: 21.917 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 746.568 | Positive charged surface: 586.392 | Negative charged surface: 160.176 | Volume: 392.375 |
Hydrophobic surface: 663.721 | Hydrophilic surface: 82.847 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |