Physical Properties | | | |
Molecular Weight: 473.624 g/mol | logS: -8.09981 | SlogP: 6.4714 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.156667 | Sterimol/B1: 2.3116 | Sterimol/B2: 4.83604 | Sterimol/B3: 4.90767 |
Sterimol/B4: 10.3725 | Sterimol/L: 17.5415 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 729.571 | Positive charged surface: 427.648 | Negative charged surface: 293.248 | Volume: 477.625 |
Hydrophobic surface: 606.149 | Hydrophilic surface: 123.422 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |