Physical Properties | | | |
Molecular Weight: 302.414 g/mol | logS: -5.15751 | SlogP: 3.829 | Reactive groups: 1 |
| | | |
Topological Properties | | | |
Globularity: 0.13305 | Sterimol/B1: 2.3826 | Sterimol/B2: 3.6527 | Sterimol/B3: 4.83166 |
Sterimol/B4: 5.00995 | Sterimol/L: 14.3502 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 493.179 | Positive charged surface: 346.762 | Negative charged surface: 146.418 | Volume: 297.25 |
Hydrophobic surface: 353.626 | Hydrophilic surface: 139.553 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 6 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |