Physical Properties | | | |
Molecular Weight: 408.539 g/mol | logS: -1.96857 | SlogP: 2.2282 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.108021 | Sterimol/B1: 2.65995 | Sterimol/B2: 4.42893 | Sterimol/B3: 5.18078 |
Sterimol/B4: 6.4281 | Sterimol/L: 16.7745 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 613.17 | Positive charged surface: 481.643 | Negative charged surface: 131.526 | Volume: 400.625 |
Hydrophobic surface: 485.594 | Hydrophilic surface: 127.576 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |