Physical Properties | | | |
Molecular Weight: 280.639 g/mol | logS: -1.22871 | SlogP: -0.4366 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0724262 | Sterimol/B1: 3.08118 | Sterimol/B2: 3.14058 | Sterimol/B3: 4.02605 |
Sterimol/B4: 5.48979 | Sterimol/L: 12.4119 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 434.332 | Positive charged surface: 234.406 | Negative charged surface: 199.926 | Volume: 209.125 |
Hydrophobic surface: 196.226 | Hydrophilic surface: 238.106 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |