Physical Properties | | | |
Molecular Weight: 355.522 g/mol | logS: -4.63845 | SlogP: 4.92557 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0867914 | Sterimol/B1: 2.83148 | Sterimol/B2: 4.79811 | Sterimol/B3: 4.82724 |
Sterimol/B4: 5.08414 | Sterimol/L: 17.2555 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 608.044 | Positive charged surface: 441.915 | Negative charged surface: 166.129 | Volume: 371.125 |
Hydrophobic surface: 471.971 | Hydrophilic surface: 136.073 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |