Physical Properties | | | |
Molecular Weight: 557.627 g/mol | logS: -8.36344 | SlogP: 5.6706 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.410488 | Sterimol/B1: 3.22987 | Sterimol/B2: 4.08075 | Sterimol/B3: 8.90704 |
Sterimol/B4: 10.0332 | Sterimol/L: 15.6453 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 828.411 | Positive charged surface: 528.027 | Negative charged surface: 300.384 | Volume: 509.75 |
Hydrophobic surface: 624.555 | Hydrophilic surface: 203.856 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |