Physical Properties | | | |
Molecular Weight: 416.433 g/mol | logS: -3.95913 | SlogP: 3.3094 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.153214 | Sterimol/B1: 2.77462 | Sterimol/B2: 3.97986 | Sterimol/B3: 5.33295 |
Sterimol/B4: 6.80737 | Sterimol/L: 15.5367 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 599.478 | Positive charged surface: 402.063 | Negative charged surface: 197.415 | Volume: 379.625 |
Hydrophobic surface: 426.611 | Hydrophilic surface: 172.867 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |