Physical Properties | | | |
Molecular Weight: 386.356 g/mol | logS: -3.29743 | SlogP: -0.3593 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0648079 | Sterimol/B1: 3.32174 | Sterimol/B2: 3.61332 | Sterimol/B3: 3.94965 |
Sterimol/B4: 6.45729 | Sterimol/L: 16.2051 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 585.219 | Positive charged surface: 385.402 | Negative charged surface: 199.817 | Volume: 333.25 |
Hydrophobic surface: 371.026 | Hydrophilic surface: 214.193 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 8 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |